| Date | Location | Result | |
| Jun 11, 2022 | B-CS, Texas | Texas A&M 4, Louisville 3 | Box score |
| Jun 10, 2022 | B-CS, Texas | Texas A&M 5, Louisville 4 | Box score |
| Jun 06, 2022 | Louisville, Ky. | Louisville 11, Michigan 9 | Box score |
| Jun 05, 2022 | Louisville, Ky. | Louisville 20, Michigan 1 | Box score |
| Jun 05, 2022 | Louisville, Ky | Louisville 8, Oregon 5 | Box score |
| Jun 04, 2022 | Louisville, Ky. | Michigan 7, Louisville 3 | Box score |
| Jun 03, 2022 | Louisville, Ky. | Louisville 7, SE Missouri State 2 | Box score |
| May 26, 2022 | Charlotte, N.C. | Georgia Tech 9, Louisville 4 | Box score |
| May 25, 2022 | Charlotte, N.C. | Pitt 6, Louisville 5 | Box score |
| May 21, 2022 | Louisville, Ky. | Louisville 11, Virginia 3 | Box score |
| May 20, 2022 | Louisville, Ky. | Virginia 16, Louisville 7 | Box score |
| May 19, 2022 | Louisville, Ky. | Louisville 4, Virginia 1 | Box score |
| May 17, 2022 | Louisville, Ky. | Louisville 10, Eastern Kentucky 3 | Box score |
| May 15, 2022 | Blacksburg, Va. | Virginia Tech 6, Louisville 4 | Box score |
| May 14, 2022 | Blacksburg, Va. | Virginia Tech 4, Louisville 3 | Box score |
| May 13, 2022 | Blacksburg, Va. | Louisville 8, Virginia Tech 1 | Box score |
| May 10, 2022 | Louisville, Ky. | Louisville 7, Indiana 2 | Box score |
| May 08, 2022 | Winston-Salem, NC | Louisville 5, Wake Forest 5 | Box score |
| May 07, 2022 | Winston-Salem, NC | Louisville 6, Wake Forest 2 | Box score |
| May 07, 2022 | Winston-Salem, NC | Wake Forest 14, Louisville 3 | Box score |
| May 03, 2022 | Nashville, Tenn. | Louisville 1, Vanderbilt 0 | Box score |
| May 01, 2022 | Louisville, Ky. | Louisville 18, Clemson 15 | Box score |
| Apr 30, 2022 | Louisville, Ky. | Louisville 10, Clemson 8 | Box score |
| Apr 29, 2022 | Louisville, Ky. | Louisville 7, Clemson 2 | Box score |
| Apr 26, 2022 | Louisville, Ky. | Louisville 11, Western Kentucky 4 | Box score |
| Apr 24, 2022 | Louisville, Ky. | Louisville 11, NC State 7 | Box score |
| Apr 23, 2022 | Louisville, Ky. | NC State 15, Louisville 10 | Box score |
| Apr 22, 2022 | Louisville, Ky. | Louisville 11, NC State 4 | Box score |
| Apr 19, 2022 | Louisville, Ky. | Louisville 4, Kentucky 2 | Box score |
| Apr 16, 2022 | Tallahassee, Fla. | Florida State 10, Louisville 9 | Box score |
| Apr 15, 2022 | Tallahassee, Fla. | Florida State 9, Louisville 4 | Box score |
| Apr 14, 2022 | Tallahassee, Fla. | Florida State 8, Louisville 1 | Box score |
| Apr 12, 2022 | Louisville, Ky. | Louisville 18, Cincinnati 10 | Box score |
| Apr 10, 2022 | Louisville, Ky. | Louisville 6, North Carolina 5 | Box score |
| Apr 09, 2022 | Louisville, Ky. | Louisville 9, North Carolina 8 | Box score |
| Apr 08, 2022 | Louisville, Ky. | North Carolina 13, Louisville 9 | Box score |
| Apr 03, 2022 | Pittsburgh, Pa. | Pitt 6, Louisville 3 | Box score |
| Apr 02, 2022 | Pittsburgh, Pa. | Louisville 14, Pitt 6 | Box score |
| Apr 02, 2022 | Pittsburgh, Pa. | Pitt 8, Louisville 7 | Box score |
| Mar 29, 2022 | Bowling Green, Ky. | Louisville 16, Western Kentucky 6 | Box score |
| Mar 27, 2022 | Brighton, Mass. | Louisville 15, Boston College 1 | Box score |
| Mar 26, 2022 | Brighton, Mass. | Louisville 10, Boston College 6 | Box score |
| Mar 25, 2022 | Brighton, Mass. | Louisville 6, Boston College 1 | Box score |
| Mar 22, 2022 | Louisville, Ky. | Lipscomb 6, Louisville 2 | Box score |
| Mar 20, 2022 | Lousville, Ky. | Louisville 7, Notre Dame 5 | Box score |
| Mar 19, 2022 | Louisville, Ky. | Louisville 8, Notre Dame 1 | Box score |
| Mar 18, 2022 | Louisville, Ky. | Louisville 16, Notre Dame 11 | Box score |
| Mar 16, 2022 | Louisville, Ky. | Louisville 11, Bellarmine 5 | Box score |
| Mar 15, 2022 | Louisville, Ky. | Louisville 12, Northern Kentucky 8 | Box score |
| Mar 13, 2022 | Louisville, Ky. | Louisville 13, Michigan 1 | Box score |
| Mar 11, 2022 | Louisville, Ky. | Michigan 16, Louisville 7 | Box score |
| Mar 11, 2022 | Louisville, Ky. | Louisville 5, Michigan 3 | Box score |
| Mar 08, 2022 | Louisville, Ky. | Louisville 9, TCU 8 | Box score |
| Mar 05, 2022 | Louisville, Ky. | Louisville 22, Akron 9 | Box score |
| Mar 05, 2022 | Louisville, Ky. | Louisville 20, Akron 6 | Box score |
| Mar 04, 2022 | Louisville, Ky. | Louisville 9, Akron 1 | Box score |
| Mar 01, 2022 | Louisville, Ky. | Louisville 7, Morehead State 5 | Box score |
| Feb 27, 2022 | Louisville, Ky. | Louisville 16, Dartmouth 3 | Box score |
| Feb 26, 2022 | Louisville, Ky. | Dartmouth 6, Louisville 4 | Box score |
| Feb 25, 2022 | Louisville, Ky. | Louisville 19, Dartmouth 5 | Box score |
| Feb 21, 2022 | Louisville, Ky. | Louisville 7, Xavier 6 | Box score |
| Feb 20, 2022 | Tampa, Fla. | UConn 9, Louisville 2 | Box score |
| Feb 19, 2022 | Tampa, Fla. | South Florida 8, Louisville 4 | Box score |
| Feb 18, 2022 | Tampa, Fla. | Louisville 8, Charlotte 7 | Box score |